Interactor 1: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Interactor 2: THOC1 (Q96FV9)
THO complex subunit 1 (Nuclear matrix protein p84) (p84N5) (hTREX84)
Gene: THOC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 26496610, 28514442, 29395067, 33961781, 31839598, 40437099, 15998806, 17190602, 23222130, 37020021, 19165146
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tho2~efThoc1, Thoc2~efThoc1, THOC2_N~efThoc1
Common GO terms GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1593
Hs

1 657
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025