Interactor 1: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A

Interactor 2: PNRC2 (Q9NPJ4)
Proline-rich nuclear receptor coactivator 2
Gene: PNRC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 25416956, 32296183, 33961781, 15604093, 23085078, unassigned1304, 24510189, 19150429, 31515488
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, ion exchange chromatography, molecular sieving, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DCP1~PNRC
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0031087 - deadenylation-independent decapping of nuclear-transcribed mRNA
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 582
Hs

1 139
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024