HitPredict

Interactor 1: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 1620
+	Hs
		1355170 SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27		ALK_HUMAN (1-1620): 0: 1883: 100.00
+	Hs
		435780 DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		666634 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		385615 DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081626 DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		609594 SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27		FGFR3_HUMAN (952-1449): 6.42e-121: 401: 26.31
+	Hs
		508250 SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411518 SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435794 SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		609471 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		FGFR3_HUMAN (952-1449): 6.42e-121: 401: 26.31
+	Hs
		508145 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411469 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Mm
		1142038 DNJA3_MOUSE (85-261): 5.32e-43: 157: 29.78		MUSK_MOUSE (983-1391): 3.56e-116: 390: 30.56
+	Hs
		507864 DNJB1_HUMAN (109-251): 2.52e-42: 152: 37.42		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		435729 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		385666 SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		385330 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		257882 DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		384289 DNJB1_HUMAN (109-251): 2.52e-42: 152: 37.42		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081563 DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03