Interactor 1: RDH11 (Q8TC12)
Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short chain dehydrogenase/reductase family 7C member 1)
Gene: RDH11

Interactor 2: RDH12 (Q96NR8)
Retinol dehydrogenase 12 (EC 1.1.1.300) (All-trans and 9-cis retinol dehydrogenase) (Short chain dehydrogenase/reductase family 7C member 2)
Gene: RDH12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 35575683, 38334954
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short
Common GO terms GO:0001523 - retinoid metabolic process
GO:0001917 - photoreceptor inner segment
GO:0004745 - all-trans-retinol dehydrogenase (NAD+) activity
GO:0005789 - endoplasmic reticulum membrane
GO:0007601 - visual perception
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 318
Hs

1 316
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Ss
+ Hv
+ At
+ Mm
+ At
+ At

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Last updated: 11Aug2025