HitPredict

Interactor 1: CSKI2 (Q8WXE0)
Caskin-2 (CASK-interacting protein 2)
Gene: CASKIN2

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19531213
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_9, SH3_2~SH3_9
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 665
+	Hs
		1191815 ANS1B_HUMAN (1-610): 1.01e-79: 288: 23.45		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		557753 CSKI2_HUMAN (1-1202): 1.75e-114: 387: 100.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		1268487 ANS1A_HUMAN (295-740): 2.77e-14: 80.3: 22.20		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		209131 CSKI2_HUMAN (1-1202): 1.75e-114: 387: 100.00		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Dm
		1360790 TNKS_DROME (2-711): 1.95e-65: 244: 13.41		Q9VA36_DROME (2-576): 1.83e-50: 190: 22.53
+	Hs
		1268522 ANS1A_HUMAN (295-740): 2.77e-14: 80.3: 22.20		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Mm
		1206702 ANS1B_MOUSE (1-610): 6.14e-79: 286: 23.75		ITSN1_MOUSE (120-519): 1.9e-19: 95.5: 14.11
+	Hs
		209098 ANS1B_HUMAN (1-610): 1.01e-79: 288: 23.45		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Mm
		1206687 ANS1B_MOUSE (1-610): 6.14e-79: 286: 23.75		ARHG7_MOUSE (228-354): 2.05e-13: 75.9: 21.88
+	Hs
		1136522 MIB1_HUMAN (2-155): 2.17e-26: 119: 22.70		SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72
+	Ce
		666223 Q93203_CAEEL (4-289): 7.47e-26: 117: 29.55		SEM5_CAEEL (2-167): 1.56e-29: 118: 21.08
+	Hs
		1078859 MIB1_HUMAN (2-155): 2.17e-26: 119: 22.70		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Ce
		1274646 Q93203_CAEEL (4-289): 7.47e-26: 117: 29.55		Q9U2T9_CAEEL (142-349): 4.59e-14: 78.1: 18.48
+	Hs
		557660 ANK2_HUMAN (315-1185): 2.96e-09: 63.9: 11.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		924484 ANK2_HUMAN (315-1185): 2.96e-09: 63.9: 11.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		257713 ANR17_HUMAN (2-104): 2.22e-10: 67.6: 28.85		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		235561 ANS1A_HUMAN (295-740): 2.77e-14: 80.3: 22.20		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82