HitPredict

Interactor 1: WWOX (Q9NZC7)
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)
Gene: WWOX

Interactor 2: WWOX (Q9NZC7)
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)
Gene: WWOX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short, WW~WW
Common GO terms GO:0001649 - osteoblast differentiation
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 15 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 414
Hs

1 414
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hv
+ Hs
+ Dm
+ Dm
+ Dm
+ Ec
+ Dm

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Last updated: 11Aug2025