HitPredict

Interactor 1: DTX3L (Q8TDB6)
E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2)
Gene: DTX3L

Interactor 2: TRIM9 (Q9C026)
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)
Gene: TRIM9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	DTC~zf-C3HC4
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0016567 - protein ubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 710
+	Hs
		1254769 DTX3L_HUMAN (1-740): 0: 1213: 100.00		TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43
+	Hs
		1192945 PAR14_HUMAN (5-134): 5.93e-42: 167: 24.81		TRI67_HUMAN (4-700): 2.1e-146: 447: 59.43
+	Hs
		1289296 DTX2_HUMAN (490-739): 9.98e-121: 377: 37.14		TRI54_HUMAN (1-56): 5.41e-09: 60.6: 36.21
+	Hs
		623444 DTX3_HUMAN (552-739): 8.69e-95: 300: 54.45		RO52_HUMAN (1-164): 2.71e-23: 105: 15.24