Interactor 1: SYLM (Q8VDC0)
Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)
Gene: Lars2

Interactor 2: SYLM (Q8VDC0)
Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)
Gene: Lars2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Anticodon_1~Anticodon_1, Anticodon_1~tRNA-synt_1, tRNA-synt_1~tRNA-synt_1, tRNA-synt_1~tRNA-synt_1_2, tRNA-synt_1_2~tRNA-synt_1_2
Common GO terms GO:0002161 - aminoacyl-tRNA deacylase activity
GO:0004823 - leucine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 902
Mm

1 902
+ Sc
+ Sc
+ Mm
+ Zm
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025