Interactor 1: SYIM (Q8BIJ6)
Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
Gene: Iars2

Interactor 2: SYIM (Q8BIJ6)
Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
Gene: Iars2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Anticodon_1~Anticodon_1, Anticodon_1~tRNA-synt_1, Anticodon_1~zf-FPG_IleRS, tRNA-synt_1~tRNA-synt_1
Common GO terms GO:0000049 - tRNA binding
GO:0002161 - aminoacyl-tRNA deacylase activity
GO:0004822 - isoleucine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1012
Mm

1 1012
+ Sc
+ Zm
+ Sc
+ Ec
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025