Interactor 1: FBX5 (Q9UKT4)
F-box only protein 5 (Early mitotic inhibitor 1)
Gene: FBXO5

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.755

The method score is based on:

Property Details
Experiments 29875408, 33306668, 33961781, 35634770, 28514442, 11988738, 11751633, 16921029, 23708001
Identification Methods enzymatic study, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0008284 - positive regulation of cell population proliferation
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 447
Hs

1 496
+ Hs
+ Mm
+ Xl
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024