Protein: PRP17
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17)

Gene: PRP17, CDC40
Organism: Homo sapiens
Interactions: 110
UniProt ID: O60508

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

251000

DHX8
ATP-dependent RNA helicase DHX8

3

20

High-throughput

0.861

High

251031

WDR83
WD repeat domain-containing protein 83

3

18

High-throughput

0.861

High

251027

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

2

18

High-throughput

0.789

High

251029

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.726

High

251048

PRP19
Pre-mRNA-processing factor 19

4

19

High-throughput

0.705

High

250984

RUXF
Small nuclear ribonucleoprotein F

4

19

High-throughput

0.697

High

251019

SNIP1
Smad nuclear-interacting protein 1

4

6

High-throughput

0.694

High

250976

IF4A3
Eukaryotic initiation factor 4A-III

1

15

High-throughput

0.691

High

250997

SNW1
SNW domain-containing protein 1

1

9

High-throughput

0.691

High

250998

DX39B
Spliceosome RNA helicase DDX39B

1

17

High-throughput

0.691

High

251002

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

9

High-throughput

0.691

High

251045

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

6

High-throughput

0.691

High

250969

RU2A
U2 small nuclear ribonucleoprotein A'

4

9

High-throughput

0.691

High

250993

ILF2
Interleukin enhancer-binding factor 2

3

6

High-throughput

0.667

High

251017

RALYL
RNA-binding Raly-like protein

3

18

High-throughput

0.667

High

251018

ZCH18
Zinc finger CCCH domain-containing protein 18

3

20

High-throughput

0.667

High

251030

USB1
U6 snRNA phosphodiesterase 1

3

2

High-throughput

0.667

High

251051

LC7L2
Putative RNA-binding protein Luc7-like 2

3

4

High-throughput

0.667

High

250983

RUXE
Small nuclear ribonucleoprotein E

3

3

High-throughput

0.662

High

250954

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.656

High

251054

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

4

3

High-throughput

0.633

High

250960

SYF2
Pre-mRNA-splicing factor SYF2

2

5

High-throughput

0.628

High

250968

RU1C
U1 small nuclear ribonucleoprotein C

2

4

High-throughput

0.628

High

250972

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

8

High-throughput

0.628

High

250988

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

10

High-throughput

0.628

High

250994

ELAV2
ELAV-like protein 2

2

3

High-throughput

0.628

High

251036

PININ
Pinin

2

3

High-throughput

0.628

High

251042

PFD2
Prefoldin subunit 2

2

4

High-throughput

0.628

High

250989

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

250987

H4
Histone H4

1

7

High-throughput

0.618

High

251001

SUZ12
Polycomb protein SUZ12

1

4

High-throughput

0.618

High

251013

PRP8
Pre-mRNA-processing-splicing factor 8

1

11

High-throughput

0.618

High

251032

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.618

High

251038

ANLN
Anillin

1

5

High-throughput

0.618

High

251040

WDR70
WD repeat-containing protein 70

1

17

High-throughput

0.618

High

250985

RUXG
Small nuclear ribonucleoprotein G

2

20

High-throughput

0.611

High

250999

RBM39
RNA-binding protein 39

2

14

High-throughput

0.611

High

250957

SPF27
Pre-mRNA-splicing factor SPF27

2

11

High-throughput

0.601

High

250964

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

20

High-throughput

0.601

High

250965

RU2B
U2 small nuclear ribonucleoprotein B''

2

18

High-throughput

0.601

High

250971

YJU2B
Probable splicing factor YJU2B

2

7

High-throughput

0.601

High

251014

LN28B
Protein lin-28 homolog B

2

9

High-throughput

0.601

High

251026

ESS2
Splicing factor ESS-2 homolog

1

3

High-throughput

0.575

High

251043

DDX41
Probable ATP-dependent RNA helicase DDX41

1

14

High-throughput

0.575

High

251016

NKAP1
Uncharacterized protein NKAPD1

2

1

High-throughput

0.574

High

156748

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.553

High

251015

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.553

High

251037

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.553

High

74405

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

17

High-throughput

0.536

High

134492

SAP18
Histone deacetylase complex subunit SAP18

1

4

High-throughput

0.536

High

250952

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

17

High-throughput

0.536

High

250956

SF3B1
Splicing factor 3B subunit 1

1

11

High-throughput

0.536

High

250966

SNRPA
U1 small nuclear ribonucleoprotein A

1

15

High-throughput

0.536

High

250970

TOP1
DNA topoisomerase 1

1

5

High-throughput

0.536

High

250978

KI67
Proliferation marker protein Ki-67

1

11

High-throughput

0.536

High

250986

SMD3
Small nuclear ribonucleoprotein Sm D3

1

20

High-throughput

0.536

High

250990

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.536

High

250996

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

251003

RNPS1
RNA-binding protein with serine-rich domain 1

1

15

High-throughput

0.536

High

251004

SF3A2
Splicing factor 3A subunit 2

1

10

High-throughput

0.536

High

251005

SF3A1
Splicing factor 3A subunit 1

1

12

High-throughput

0.536

High

251006

SRSF7
Serine/arginine-rich splicing factor 7

1

17

High-throughput

0.536

High

251007

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

14

High-throughput

0.536

High

251009

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

11

High-throughput

0.536

High

251021

CCD12
Coiled-coil domain-containing protein 12

1

3

High-throughput

0.536

High

251039

DJC17
DnaJ homolog subfamily C member 17

1

17

High-throughput

0.536

High

251044

RALY
RNA-binding protein Raly

1

9

High-throughput

0.536

High

251049

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

6

High-throughput

0.536

High

251052

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

4

High-throughput

0.536

High

251053

RTCB
RNA-splicing ligase RtcB homolog

1

2

High-throughput

0.536

High

192526

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

250962

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.501

High

250953

DNJA2
DnaJ homolog subfamily A member 2

1

11

High-throughput

0.489

High

240227

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

247545

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

250955

TAD2A
Transcriptional adapter 2-alpha

1

20

High-throughput

0.479

High

250958

RNF8
E3 ubiquitin-protein ligase RNF8

1

11

Small-scale

0.479

High

250959

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.479

High

250961

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

250973

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

250975

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

250980

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

250981

MECP2
Methyl-CpG-binding protein 2

1

11

High-throughput

0.479

High

250982

MGN
Protein mago nashi homolog

1

3

High-throughput

0.479

High

250991

VIGLN
Vigilin

1

18

High-throughput

0.479

High

250992

EP300
Histone acetyltransferase p300

1

9

High-throughput

0.479

High

251008

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

251012

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.479

High

251022

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

251023

FUBP1
Far upstream element-binding protein 1

1

16

High-throughput

0.479

High

251028

CDC5L
Cell division cycle 5-like protein

1

13

High-throughput

0.479

High

251041

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

251047

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.479

High

251050

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

20

High-throughput

0.479

High

251025

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

250977

EPS15
Epidermal growth factor receptor substrate 15

1

7

High-throughput

0.457

High

71545

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

20

High-throughput

0.445

High

250995

TRAF2
TNF receptor-associated factor 2

1

8

Small-scale

0.445

High

250963

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.437

High

250979

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.437

High

251033

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.437

High

251034

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

251035

RHBT2
Rho-related BTB domain-containing protein 2

1

8

High-throughput

0.437

High

251046

HECD1
E3 ubiquitin-protein ligase HECTD1

1

13

High-throughput

0.437

High

250967

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.426

High

251010

ODFP2
Outer dense fiber protein 2

1

13

High-throughput

0.407

High

251011

CE170
Centrosomal protein of 170 kDa

1

18

High-throughput

0.407

High

250974

CD44
CD44 antigen

2

0

High-throughput

0.328

High

251024

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

251020

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025