HitPredict

Interactor 1: Q9V3V3 (Q9V3V3)
Pez, isoform A (Pez, isoform B) (Protein tyrosine phosphatase Pez)
Gene: Pez

Interactor 2: KIBRA (Q9VFG8)
Protein kibra
Gene: KIBRA

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	22305752, 25814387
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035332 - positive regulation of hippo signaling GO:0045463 - R8 cell development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1252 Dm			1 1288
+	Hs
		1076877 PTN14_HUMAN (1-1252): 0: 666: 22.50		WWC2_HUMAN (45-1156): 8.51e-166: 528: 28.91
+	Hs
		1087899 PTN21_HUMAN (1-1252): 0: 625: 23.78		WWC2_HUMAN (45-1156): 8.51e-166: 528: 28.91
+	Hs
		1076894 PTN14_HUMAN (1-1252): 0: 666: 22.50		KIBRA_HUMAN (52-1156): 3.02e-150: 484: 28.43
+	Hs
		1087910 PTN21_HUMAN (1-1252): 0: 625: 23.78		KIBRA_HUMAN (52-1156): 3.02e-150: 484: 28.43
+	Dm
		1359218 Q9V3V3_DROME (1-1252): 0: 747: 100.00		SUDX_DROME (40-168): 2.01e-30: 132: 28.68
+	Hs
		719536 MERL_HUMAN (1-498): 9.61e-121: 389: 17.68		KIBRA_HUMAN (52-1156): 3.02e-150: 484: 28.43
+	Hs
		1076872 PTN14_HUMAN (1-1252): 0: 666: 22.50		MAGI3_HUMAN (32-153): 1.41e-38: 159: 37.71
+	Hs
		1076909 PTN14_HUMAN (1-1252): 0: 666: 22.50		MAGI1_HUMAN (50-141): 6.42e-35: 147: 36.54
+	Hs
		808641 PTN14_HUMAN (1-1252): 0: 666: 22.50		YAP1_HUMAN (38-152): 2.99e-34: 140: 29.13
+	Hs
		125485 PTN14_HUMAN (1-1252): 0: 666: 22.50		WWP2_HUMAN (34-200): 2.43e-29: 128: 23.95
+	Hs
		1076918 PTN14_HUMAN (1-1252): 0: 666: 22.50		WWP1_HUMAN (9-176): 1.4e-22: 106: 23.81
+	Hs
		1076933 PTN14_HUMAN (1-1252): 0: 666: 22.50		WWOX_HUMAN (48-134): 3.39e-23: 105: 32.18
+	Hs
		808660 PTN21_HUMAN (1-1252): 0: 625: 23.78		YAP1_HUMAN (38-152): 2.99e-34: 140: 29.13
+	Hs
		1087931 PTN21_HUMAN (1-1252): 0: 625: 23.78		WWP1_HUMAN (9-176): 1.4e-22: 106: 23.81
+	Hs
		48519 E41L5_HUMAN (16-518): 3.7e-138: 440: 19.88		ESYT2_HUMAN (307-821): 3.3e-72: 262: 16.79
+	Hs
		1238356 E41L5_HUMAN (16-518): 3.7e-138: 440: 19.88		SYT2_HUMAN (674-818): 4.84e-20: 96.4: 17.50
+	Hs
		719410 MERL_HUMAN (1-498): 9.61e-121: 389: 17.68		YAP1_HUMAN (38-152): 2.99e-34: 140: 29.13
+	Hs
		125188 MERL_HUMAN (1-498): 9.61e-121: 389: 17.68		WWP2_HUMAN (34-200): 2.43e-29: 128: 23.95
+	Hs
		546967 EZRI_HUMAN (17-437): 4.35e-120: 387: 16.59		NEDD4_HUMAN (2-217): 1.44e-15: 84.6: 17.51
+	Hs
		719588 MERL_HUMAN (1-498): 9.61e-121: 389: 17.68		NED4L_HUMAN (2-258): 3.97e-10: 66.5: 14.18