HitPredict

Interactor 1: UBE2C (O00762)
Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C)
Gene: UBE2C

Interactor 2: APC11 (Q9NYG5)
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein)
Gene: ANAPC11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.997

The method score is based on:

Property Details
Experiments 32905768, 22193957, 23707760, 23670162, 25246557, 23288039, 22205987, 11739784, 25161877, 23972993, 25490258, 25959309, 25825779, 25306923, 26329581, 27120157, 21700221, 27114510, 27509861, 27522463 and 44 others

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Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-ANAPC11
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 6 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 179
Hs

1 84
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024