HitPredict

Interactor 1: DDX1 (Q92499)
ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB)
Gene: DDX1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 626
+	Hs
		1363292 DDX1_HUMAN (1-740): 0: 571: 100.00		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		807587 IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		1340769 DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		141604 DDX3X_HUMAN (1-380): 1.78e-41: 163: 13.47		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		1369406 DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71		NLE1_HUMAN (181-575): 2.23e-63: 218: 12.47
+	Hs
		1369337 DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		193129 DDX3Y_HUMAN (1-380): 7e-41: 161: 13.97		POC1A_HUMAN (391-623): 3.95e-49: 178: 12.45
+	Hs
		141400 DDX3X_HUMAN (1-380): 1.78e-41: 163: 13.47		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		965133 DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		608525 DDX5_HUMAN (1-381): 9.96e-35: 142: 11.45		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		1369343 DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		608695 DDX5_HUMAN (1-381): 9.96e-35: 142: 11.45		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		807338 IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		807526 IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83