HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: H2A1H (Q96KK5)
Histone H2A type 1-H (H2A-clustered histone 12) (Histone H2A/s)
Gene: H2AC12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21951318
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 128
+	Hs
		502460 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		H2A1_HUMAN (1-128): 1.31e-66: 199: 100.00
+	Hs
		591756 ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00		H2AX_HUMAN (1-123): 3.76e-63: 190: 95.12
+	Hs
		396803 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		H2A1J_HUMAN (1-128): 5.26e-67: 200: 99.22
+	Hs
		396216 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		H2A2C_HUMAN (1-125): 1.35e-64: 194: 97.60
+	Hs
		395434 ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56		H2AX_HUMAN (1-123): 3.76e-63: 190: 95.12
+	Hs
		404376 GCR_HUMAN (3-495): 1.13e-103: 330: 22.64		H2A1J_HUMAN (1-128): 5.26e-67: 200: 99.22
+	Hs
		520616 RARA_HUMAN (52-505): 3.56e-105: 324: 23.74		H2A1C_HUMAN (1-128): 1.2e-66: 199: 98.44
+	Hs
		520626 RARA_HUMAN (52-505): 3.56e-105: 324: 23.74		H2A1A_HUMAN (1-125): 2.72e-66: 198: 95.20
+	Hs
		520602 RARA_HUMAN (52-505): 3.56e-105: 324: 23.74		H2A2B_HUMAN (1-128): 1.07e-65: 196: 95.31
+	Hs
		520340 ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59		H2AJ_HUMAN (1-125): 1.56e-64: 193: 96.80