HitPredict

Interactor 1: SMD2 (Q9VI10)
Probable small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SMD2

Interactor 2: Q9VRT7 (Q9VRT7)
U6 snRNA-associated Sm-like protein LSm5
Gene: BcDNA:RE60135

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005681 - spliceosomal complex GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 119 Dm			1 91
+	Hs
		912601 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Hs
		912210 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Hs
		911610 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Dm
		1213198 Q8IMX8_DROME (12-111): 3.6e-33: 113: 31.68		Q9VRT7_DROME (1-91): 9.35e-33: 110: 100.00
+	Hs
		912141 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		LSM3_HUMAN (7-86): 4.38e-23: 86.5: 24.44
+	Hs
		911607 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Dm
		1367659 SMD2_DROME (1-119): 2.1e-46: 147: 100.00		RUXG_DROME (19-84): 1.53e-13: 61.5: 27.27
+	Sc
		768253 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		LSM5_YEAST (9-88): 1.54e-23: 87.3: 38.82
+	Sc
		884829 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		LSM3_YEAST (12-91): 1.93e-22: 84.6: 21.43
+	Sc
		986610 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		RUXE_YEAST (4-86): 1.8e-22: 84.6: 21.74
+	Hs
		912587 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		LSM7_HUMAN (19-85): 1.09e-14: 64.9: 26.39
+	Hs
		912023 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73
+	Sp
		1378244 LSM3_SCHPO (18-111): 5.54e-31: 107: 29.79		LSM3_SCHPO (11-86): 2.5e-23: 86.9: 20.93
+	Hs
		68410 SMD2_HUMAN (3-113): 6.83e-41: 133: 90.09		RUXGL_HUMAN (19-84): 2.58e-12: 58.4: 22.73
+	Hs
		912202 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		LSM7_HUMAN (19-85): 1.09e-14: 64.9: 26.39
+	Hs
		912020 LSM3_HUMAN (12-111): 9.41e-36: 119: 28.00		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73
+	Sc
		768245 LSM3_YEAST (25-111): 3.84e-24: 89.8: 28.74		LSM5_YEAST (9-88): 1.54e-23: 87.3: 38.82
+	Sc
		884818 LSM3_YEAST (25-111): 3.84e-24: 89.8: 28.74		LSM3_YEAST (12-91): 1.93e-22: 84.6: 21.43
+	Sc
		865981 SMD2_YEAST (3-113): 7.77e-34: 115: 54.05		LSM7_YEAST (21-86): 4.96e-11: 56.1: 28.38
+	Sc
		865977 LSM3_YEAST (25-111): 3.84e-24: 89.8: 28.74		LSM7_YEAST (21-86): 4.96e-11: 56.1: 28.38