HitPredict

Interactor 1: FGF14 (Q92915)
Fibroblast growth factor 14 (FGF-14) (Fibroblast growth factor homologous factor 4) (FHF-4)
Gene: FGF14

Interactor 2: SCN8A (Q9UQD0)
Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)
Gene: SCN8A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	25659151, 29359916, 22364545
Identification Methods	pull down, affinity chromatography technology, split firefly luciferase complementation, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 1980
+	Mm
		73091 FGF14_MOUSE (1-247): 5.24e-120: 343: 98.38		SCN2A_MOUSE (1-1979): 0: 1905: 73.20
+	Hs
		1370526 FGF13_HUMAN (1-247): 1.21e-110: 320: 67.61		SCN2A_HUMAN (1-1979): 0: 1916: 73.33
+	Hs
		771747 FGF12_HUMAN (1-246): 1.84e-107: 311: 70.97		SCN1A_HUMAN (1-1968): 0: 1840: 72.73
+	Hs
		1127632 FGF14_HUMAN (1-247): 1.4e-119: 342: 100.00		SCN5A_HUMAN (3-1953): 0: 1760: 61.09
+	Hs
		1127630 FGF13_HUMAN (1-247): 1.21e-110: 320: 67.61		SCN5A_HUMAN (3-1953): 0: 1760: 61.09
+	Hs
		961173 FGF12_HUMAN (1-246): 1.84e-107: 311: 70.97		SCN5A_HUMAN (3-1953): 0: 1760: 61.09
+	Hs
		1127631 FGF11_HUMAN (3-225): 2.4e-100: 293: 61.61		SCN5A_HUMAN (3-1953): 0: 1760: 61.09