HitPredict

Interactor 1: DYLT (Q94524)
Dynein light chain Tctex-type (TCTEX-1 protein homolog)
Gene: Dlc90F

Interactor 2: Q9VH45 (Q9VH45)
Dynein light chain (RE37471p) (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform C)
Gene: DmelCG5359

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	14605208, 37061542, unassigned2874
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Tctex-1~Tctex-1
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex GO:0007018 - microtubule-based movement GO:0030286 - dynein complex GO:0045505 - dynein intermediate chain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 111 Dm			1 173
+	Hs
		991893 DYLT1_HUMAN (4-111): 1.1e-45: 144: 71.30		DYT2B_HUMAN (31-173): 1.89e-53: 168: 32.64
+	Hs
		907976 DYLT3_HUMAN (6-111): 2.39e-43: 138: 48.11		DYT2B_HUMAN (31-173): 1.89e-53: 168: 32.64
+	Dm
		1263924 DYLT_DROME (1-111): 5.28e-45: 143: 100.00		Q7K035_DROME (18-172): 2.67e-49: 159: 19.75
+	Hs
		907967 DYLT1_HUMAN (4-111): 1.1e-45: 144: 71.30		DYLT3_HUMAN (62-170): 2.12e-46: 149: 21.10
+	Cr
		265679 O64980_CHLRE (1-111): 3.17e-46: 146: 55.86		O64980_CHLRE (61-170): 3.24e-45: 146: 27.93
+	Hs
		991826 DYLT1_HUMAN (4-111): 1.1e-45: 144: 71.30		DYLT1_HUMAN (64-170): 1.84e-45: 146: 22.43
+	Hs
		907964 DYLT3_HUMAN (6-111): 2.39e-43: 138: 48.11		DYLT3_HUMAN (62-170): 2.12e-46: 149: 21.10
+	Dm
		1374830 DYLT_DROME (1-111): 5.28e-45: 143: 100.00		DYLT_DROME (62-170): 3.8e-44: 143: 22.94
+	Hs
		991856 DYLT1_HUMAN (4-111): 1.1e-45: 144: 71.30		DYLT4_HUMAN (33-171): 3.8e-41: 139: 30.94
+	Hs
		1206058 DYT2B_HUMAN (1-108): 8.73e-37: 123: 23.85		DYLT4_HUMAN (33-171): 3.8e-41: 139: 30.94