HitPredict

Interactor 1: DYLT3 (P51808)
Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)
Gene: DYNLT3

Interactor 2: DYT2B (Q8WW35)
Dynein light chain Tctex-type protein 2B (Tctex1 domain-containing protein 2)
Gene: DYNLT2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tctex-1~Tctex-1
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex GO:0007018 - microtubule-based movement GO:0045505 - dynein intermediate chain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 142
+	Hs
		991893 DYLT1_HUMAN (1-114): 9.89e-46: 145: 53.51		DYT2B_HUMAN (1-142): 3.9e-67: 201: 100.00
+	Dm
		1374848 DYLT_DROME (5-114): 3.37e-42: 136: 46.36		Q9VH45_DROME (12-142): 1.8e-50: 160: 32.84
+	Hs
		991856 DYLT1_HUMAN (1-114): 9.89e-46: 145: 53.51		DYLT4_HUMAN (7-140): 3.13e-44: 145: 33.58
+	Hs
		907964 DYLT3_HUMAN (1-116): 4.52e-47: 148: 100.00		DYLT3_HUMAN (32-139): 2.78e-43: 140: 22.22
+	Cr
		265679 O64980_CHLRE (1-114): 7.18e-46: 145: 45.61		O64980_CHLRE (31-139): 6.71e-43: 139: 26.55
+	Hs
		907967 DYLT3_HUMAN (1-116): 4.52e-47: 148: 100.00		DYLT1_HUMAN (35-139): 5.64e-41: 134: 29.36
+	Hs
		991826 DYLT1_HUMAN (1-114): 9.89e-46: 145: 53.51		DYLT1_HUMAN (35-139): 5.64e-41: 134: 29.36
+	Hs
		1206058 DYT2B_HUMAN (2-111): 1.38e-36: 123: 21.24		DYLT4_HUMAN (7-140): 3.13e-44: 145: 33.58
+	Dm
		1374830 DYLT_DROME (5-114): 3.37e-42: 136: 46.36		DYLT_DROME (34-139): 6.49e-40: 131: 24.55
+	Dm
		1263924 DYLT_DROME (5-114): 3.37e-42: 136: 46.36		Q7K035_DROME (28-141): 2.05e-37: 127: 26.09