HitPredict

Interactor 1: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Interactor 2: RUB1 (Q9SHE7)
Ubiquitin-NEDD8-like protein RUB1 [Cleaved into: Ubiquitin; NEDD8-like protein RUB1 (Ubiquitin-related protein 1) (AtRUB1)]
Gene: RUB1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	15319484, 22893627
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~ubiquitin, Cullin_Nedd8~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0009733 - response to auxin
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 738 At			1 156
+	At
		1167861 CUL1_ARATH (1-738): 0: 839: 100.00		UBQ3_ARATH (1-152): 1.6e-59: 188: 80.92
+	Hs
		507941 CUL3_HUMAN (1-738): 0: 799: 30.09		UBC_HUMAN (1-152): 3.53e-57: 190: 78.95
+	At
		1456480 CUL3A_ARATH (5-738): 0: 797: 33.92		RUB1_ARATH (1-156): 1.51e-60: 185: 100.00
+	Hs
		507942 CUL4A_HUMAN (13-738): 0: 791: 34.61		UBC_HUMAN (1-152): 3.53e-57: 190: 78.95
+	At
		1423046 CUL3B_ARATH (2-738): 0: 785: 31.74		RUB1_ARATH (1-156): 1.51e-60: 185: 100.00
+	Hs
		507190 CUL4B_HUMAN (12-738): 0: 778: 32.93		UBB_HUMAN (1-152): 7.21e-62: 191: 78.95
+	Hs
		507943 CUL4B_HUMAN (12-738): 0: 778: 32.93		UBC_HUMAN (1-152): 3.53e-57: 190: 78.95
+	At
		1341732 CUL1_ARATH (1-738): 0: 839: 100.00		RUB2_ARATH (77-155): 2.8e-24: 93.4: 59.49
+	Hs
		507939 CUL1_HUMAN (4-738): 0: 732: 30.53		UBC_HUMAN (1-152): 3.53e-57: 190: 78.95
+	Mm
		509303 CUL3_MOUSE (1-738): 0: 798: 30.09		UBC_MOUSE (1-105): 1.25e-30: 117: 82.86
+	Rn
		81586 CUL3_RAT (1-738): 0: 798: 30.09		UBC_RAT (1-105): 1.49e-30: 117: 80.95
+	Rn
		74716 B2RYJ3_RAT (13-738): 0: 787: 33.52		UBC_RAT (1-105): 1.49e-30: 117: 80.95
+	Hs
		507940 CUL2_HUMAN (1-738): 0: 691: 27.05		UBC_HUMAN (1-152): 3.53e-57: 190: 78.95
+	Sp
		151350 CUL1_SCHPO (3-738): 0: 683: 27.94		UBI4P_SCHPO (1-152): 1.28e-57: 185: 79.61
+	Rn
		73323 B1WBY1_RAT (4-738): 0: 732: 30.53		UBC_RAT (1-105): 1.49e-30: 117: 80.95
+	Mm
		509270 CUL2_MOUSE (1-738): 0: 697: 26.53		UBC_MOUSE (1-105): 1.25e-30: 117: 82.86
+	Hs
		508379 CUL5_HUMAN (3-738): 0: 618: 24.14		UBC_HUMAN (1-152): 3.53e-57: 190: 78.95
+	Rn
		1224528 CUL5_RAT (3-738): 0: 617: 24.27		UBC_RAT (1-105): 1.49e-30: 117: 80.95
+	Mm
		509271 CUL5_MOUSE (3-738): 0: 612: 24.40		UBC_MOUSE (1-105): 1.25e-30: 117: 82.86