HitPredict

Interactor 1: Q9N5V3 (Q9N5V3)
Importin N-terminal domain-containing protein
Gene: imb-3

Interactor 2: Q9XWK3 (Q9XWK3)
Nucleoporin p58/p45
Gene: npp-4

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	18692475, unassigned701
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1092 Ce			1 538
+	Hs
		127197 IPO5_HUMAN (2-1090): 0: 647: 35.31		NU214_HUMAN (6-510): 3.95e-10: 65: 11.59
+	Ce
		136533 Q9N5V3_CAEEL (1-1092): 0: 620: 100.00		O01576_CAEEL (5-495): 4.26e-14: 77.3: 18.34
+	Sc
		687985 IMB3_YEAST (6-1078): 1.33e-128: 420: 24.22		NUP49_YEAST (5-326): 2.73e-14: 77.3: 17.98
+	Sc
		687969 IMB3_YEAST (6-1078): 1.33e-128: 420: 24.22		NU145_YEAST (82-440): 1.22e-12: 73: 13.41
+	Sc
		687954 IMB3_YEAST (6-1078): 1.33e-128: 420: 24.22		NU159_YEAST (2-485): 1.45e-12: 72.7: 12.91
+	Sc
		687967 IMB3_YEAST (6-1078): 1.33e-128: 420: 24.22		NUP57_YEAST (11-220): 1.82e-12: 71.9: 25.46
+	Sc
		687987 IMB3_YEAST (6-1078): 1.33e-128: 420: 24.22		NU116_YEAST (38-517): 4.84e-10: 64.6: 13.97
+	Sc
		687986 IMB3_YEAST (6-1078): 1.33e-128: 420: 24.22		NU100_YEAST (32-535): 2.6e-09: 62.3: 13.50
+	Sc
		767710 IMB4_YEAST (1-1091): 8.6e-112: 375: 17.20		NUP49_YEAST (5-326): 2.73e-14: 77.3: 17.98
+	Sc
		767656 IMB4_YEAST (1-1091): 8.6e-112: 375: 17.20		NU159_YEAST (2-485): 1.45e-12: 72.7: 12.91
+	Sc
		767683 IMB4_YEAST (1-1091): 8.6e-112: 375: 17.20		NUP57_YEAST (11-220): 1.82e-12: 71.9: 25.46
+	Sc
		767713 IMB4_YEAST (1-1091): 8.6e-112: 375: 17.20		NU116_YEAST (38-517): 4.84e-10: 64.6: 13.97
+	Sc
		767712 IMB4_YEAST (1-1091): 8.6e-112: 375: 17.20		NU100_YEAST (32-535): 2.6e-09: 62.3: 13.50
+	Ce
		248186 O62332_CAEEL (349-1021): 5.01e-45: 178: 10.98		Q9XWK3_CAEEL (1-538): 1.27e-70: 237: 100.00
+	Tt
		101907 G0SGZ5_CHATD (9-814): 6.08e-82: 289: 17.18		NU145_CHATD (14-345): 2.65e-10: 65.3: 14.11
+	Hs
		858024 TNPO1_HUMAN (274-1089): 1.23e-73: 264: 12.31		NUP98_HUMAN (38-364): 7.96e-16: 83.1: 16.37
+	Hs
		155553 TNPO2_HUMAN (206-1089): 1.02e-67: 247: 10.70		NUP98_HUMAN (38-364): 7.96e-16: 83.1: 16.37
+	Hs
		727300 TNPO1_HUMAN (274-1089): 1.23e-73: 264: 12.31		NU214_HUMAN (6-510): 3.95e-10: 65: 11.59
+	Ce
		248176 O62332_CAEEL (349-1021): 5.01e-45: 178: 10.98		Q21295_CAEEL (9-158): 4.2e-12: 70.7: 24.00
+	Ce
		248185 O62332_CAEEL (349-1021): 5.01e-45: 178: 10.98		Q9U3B9_CAEEL (58-277): 3.97e-10: 64.6: 22.03