Interactor 1: CATL1 (Q95029)
Cathepsin L1 (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]
Gene: CtsL1

Interactor 2: CATF (Q9VN93)
Cathepsin F (EC 3.4.22.41) (Cysteine proteinase CtsF)
Gene: CtsF

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Inhibitor_I29~Inhibitor_I29, Inhibitor_I29~Peptidase_C1, Peptidase_C1~Peptidase_C1
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005764 - lysosome
GO:0008234 - cysteine-type peptidase activity
GO:0045169 - fusome
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 371
Dm

1 614
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025