HitPredict

Interactor 1: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: RN114 (Q9Y508)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: RNF114

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 22493164
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_2~zf_C2HC_14
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 522
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1 228
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024