HitPredict

Interactor 1: PCDGA (Q9Y5H3)
Protocadherin gamma-A10 (PCDH-gamma-A10)
Gene: PCDHGA10

Interactor 2: PCDA8 (Q9Y5H6)
Protocadherin alpha-8 (PCDH-alpha-8)
Gene: PCDHA8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 936 Hs			1 950
+	Hs
		1357414 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDA4_HUMAN (1-950): 0: 1057: 80.95
+	Hs
		1378046 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDAB_HUMAN (1-950): 0: 1055: 81.47
+	Hs
		1378033 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDG7_HUMAN (1-898): 0: 935: 37.98
+	Hs
		1378040 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDG4_HUMAN (1-898): 0: 935: 38.13
+	Hs
		1378022 PCDG8_HUMAN (1-921): 0: 1045: 76.66		PCDG9_HUMAN (1-898): 0: 942: 37.72
+	Hs
		1378028 PCDG8_HUMAN (1-921): 0: 1045: 76.66		PCDG5_HUMAN (1-898): 0: 939: 39.33
+	Hs
		1357394 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDGK_HUMAN (27-898): 0: 953: 39.53
+	Hs
		1378029 PCDG8_HUMAN (1-921): 0: 1045: 76.66		PCDG4_HUMAN (1-898): 0: 935: 38.13
+	Hs
		1378035 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDG6_HUMAN (1-898): 0: 946: 38.63
+	Hs
		1378024 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDG9_HUMAN (1-898): 0: 942: 37.72
+	Hs
		1378037 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDG5_HUMAN (1-898): 0: 939: 39.33
+	Hs
		1378032 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDG7_HUMAN (1-898): 0: 935: 37.98
+	Hs
		1378016 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDGE_HUMAN (25-898): 0: 890: 37.32
+	Hs
		1328456 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDC1_HUMAN (6-447): 3.07e-79: 279: 24.18
+	Hs
		1378044 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDA9_HUMAN (3-374): 2.15e-58: 219: 23.26
+	Hs
		1378039 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDG3_HUMAN (2-342): 2.86e-67: 244: 24.00
+	Hs
		231362 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDGC_HUMAN (1-342): 1.98e-66: 242: 23.94
+	Hs
		1378001 PCDG4_HUMAN (1-921): 0: 1030: 74.16		PCDGJ_HUMAN (2-337): 4.02e-61: 226: 21.65
+	Hs
		1357424 PCDGA_HUMAN (1-921): 0: 1059: 100.00		PCDAC_HUMAN (3-266): 2.2e-34: 144: 20.22