HitPredict

Interactor 1: P2C77 (O04719)
Protein phosphatase 2C 77 (AtPP2C77) (EC 3.1.3.16) (Protein ABSCISIC ACID-INSENSITIVE 2) (Protein phosphatase 2C ABI2) (PP2C ABI2)
Gene: ABI2

Interactor 2: SRK2E (Q940H6)
Serine/threonine-protein kinase SRK2E (EC 2.7.11.1) (Protein OPEN STOMATA 1) (SNF1-related kinase 2.6) (SnRK2.6) (Serine/threonine-protein kinase OST1)
Gene: SRK2E

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.975

Property	Details
Experiments	19955427, 20561261, 22730405, 22516825, 20729862, 19924127, 22116026, 21885535, 19805022
Identification Methods	two hybrid, protein complementation assay, affinity chromatography technology, unspecified method, enzymatic study, pull down, phosphatase assay
Interaction Type	direct interaction, physical association, dephosphorylation reaction

Property	Details
Interacting Pfam domains	PP2C~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0006970 - response to osmotic stress GO:0009414 - response to water deprivation GO:0009737 - response to abscisic acid GO:0009738 - abscisic acid-activated signaling pathway and 1 others more... GO:1902456 - regulation of stomatal opening
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 423 At			1 362
+	At
		138617 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2J_ARATH (18-349): 2.89e-148: 423: 66.27
+	At
		138629 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		CDPKC_ARATH (2-361): 7.29e-139: 405: 27.87
+	At
		138628 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2I_ARATH (1-362): 6.35e-139: 400: 79.06
+	At
		138645 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2H_ARATH (18-322): 8.89e-138: 397: 74.51
+	At
		138644 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2B_ARATH (18-328): 1.79e-136: 394: 74.36
+	At
		138652 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2F_ARATH (18-328): 7.12e-136: 392: 70.79
+	At
		138623 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2A_ARATH (18-325): 2.78e-135: 391: 75.73
+	At
		138627 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		SRK2D_ARATH (5-362): 6.1e-135: 390: 77.37
+	At
		138640 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		CIPKN_ARATH (18-343): 3.38e-131: 385: 33.43
+	At
		829535 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		SRK2C_ARATH (18-318): 1.95e-150: 429: 75.42
+	At
		829513 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		SRK2E_ARATH (1-362): 7.62e-148: 423: 100.00
+	At
		829496 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		SRK2I_ARATH (1-362): 6.35e-139: 400: 79.06
+	At
		829544 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		CDPKL_ARATH (6-360): 1.63e-134: 395: 28.04
+	At
		794945 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		SRK2A_ARATH (18-325): 2.78e-135: 391: 75.73
+	At
		829494 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		KIN10_ARATH (20-333): 4.84e-133: 391: 40.25
+	At
		829495 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		SRK2D_ARATH (5-362): 6.1e-135: 390: 77.37
+	At
		1107194 P2C07_ARATH (27-421): 1.35e-121: 364: 49.03		SRK2I_ARATH (1-362): 6.35e-139: 400: 79.06
+	At
		1107175 P2C07_ARATH (27-421): 1.35e-121: 364: 49.03		SRK2D_ARATH (5-362): 6.1e-135: 390: 77.37
+	At
		138655 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		CIPK8_ARATH (20-300): 4.36e-66: 217: 42.03
+	At
		187499 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		CIPKB_ARATH (20-279): 4.04e-62: 206: 41.54