HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37059091, 19596235
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 1834
+	Hs
		142581 IMA3_HUMAN (1-521): 3.11e-157: 459: 85.80		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		910981 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		179065 IMA6_HUMAN (4-520): 2.03e-133: 399: 46.73		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		911302 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		142498 IMA3_HUMAN (1-521): 3.11e-157: 459: 85.80		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		853945 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		861078 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90