HitPredict

Interactor 1: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 236 Hs			1 147
+	Hs
		906750 BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00		UB2D1_HUMAN (1-147): 3.33e-83: 242: 91.84
+	Hs
		982291 BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00		UB2D2_HUMAN (1-147): 7.67e-83: 241: 93.20
+	Hs
		957171 BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00		UB2D3_HUMAN (1-147): 8.57e-82: 238: 91.84
+	Hs
		909378 BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00		UB2E1_HUMAN (4-146): 3.9e-73: 218: 64.34
+	Hs
		957819 BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00		UBE2N_HUMAN (4-147): 2.31e-69: 207: 46.53
+	Hs
		906737 BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47		UB2D1_HUMAN (1-147): 3.33e-83: 242: 91.84
+	Hs
		982277 BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47		UB2D2_HUMAN (1-147): 7.67e-83: 241: 93.20
+	Hs
		957158 BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47		UB2D3_HUMAN (1-147): 8.57e-82: 238: 91.84
+	Hs
		909368 BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47		UB2E1_HUMAN (4-146): 3.9e-73: 218: 64.34
+	Hs
		906793 BIRC6_HUMAN (1-185): 3.04e-36: 137: 20.31		UB2D1_HUMAN (1-147): 3.33e-83: 242: 91.84
+	Hs
		906733 MIB2_HUMAN (37-234): 1.21e-28: 115: 19.34		UB2D1_HUMAN (1-147): 3.33e-83: 242: 91.84
+	Hs
		982273 MIB2_HUMAN (37-234): 1.21e-28: 115: 19.34		UB2D2_HUMAN (1-147): 7.67e-83: 241: 93.20
+	At
		762751 RGLG3_ARATH (53-234): 4.97e-24: 100: 15.61		UBC8_ARATH (1-147): 4.29e-83: 242: 80.27
+	Hs
		906723 RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78		UB2D1_HUMAN (1-147): 3.33e-83: 242: 91.84
+	At
		762748 LUL3_ARATH (86-233): 1.32e-23: 99.3: 17.76		UBC8_ARATH (1-147): 4.29e-83: 242: 80.27
+	Hs
		982264 RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78		UB2D2_HUMAN (1-147): 7.67e-83: 241: 93.20
+	At
		1342035 RGLG3_ARATH (53-234): 4.97e-24: 100: 15.61		UBC30_ARATH (1-147): 1.12e-81: 238: 81.63
+	Hs
		957149 RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78		UB2D3_HUMAN (1-147): 8.57e-82: 238: 91.84
+	Hs
		957808 MIB2_HUMAN (37-234): 1.21e-28: 115: 19.34		UBE2N_HUMAN (4-147): 2.31e-69: 207: 46.53
+	Hs
		957804 RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78		UBE2N_HUMAN (4-147): 2.31e-69: 207: 46.53