Protein: BIRC8
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)

Gene: BIRC8
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q96P09

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0008270 - zinc ion binding
GO:0031398 - positive regulation of protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

936965

CASP9
Caspase-9

5

20

Small-scale

0.925

High

1399324

DBLOH
Diablo IAP-binding mitochondrial protein

4

11

Small-scale

0.892

High

1022778

XIAP
E3 ubiquitin-protein ligase XIAP

3

15

High-throughput

0.861

High

1399323

CDK19
Cyclin-dependent kinase 19

2

9

High-throughput

0.789

High

906750

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

High-throughput

0.698

High

909378

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

High-throughput

0.698

High

957171

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

High-throughput

0.698

High

957819

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.698

High

982291

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.698

High

1103930

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.698

High

1383923

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1399328

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

440683

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.691

High

216788

HTRA2
Serine protease HTRA2, mitochondrial

3

15

High-throughput

0.667

High

359714

DHE3
Glutamate dehydrogenase 1, mitochondrial

3

1

High-throughput

0.667

High

957650

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

20

High-throughput

0.621

High

952461

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

20

High-throughput

0.555

High

238940

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

4

High-throughput

0.536

High

1365842

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

7

High-throughput

0.536

High

1399326

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

1399327

LIMC1
LIM and calponin homology domains-containing protein 1

1

4

High-throughput

0.536

High

75524

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

76434

B4DUB1
cyclin-dependent kinase

1

8

High-throughput

0.514

High

1399322

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

1399325

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.513

High

702034

TMOD1
Tropomodulin-1

1

6

High-throughput

0.489

High

1145913

RBP1
RalA-binding protein 1

1

6

High-throughput

0.489

High

1292186

LIPB1
Liprin-beta-1

1

3

High-throughput

0.489

High

164627

TNPO2
Transportin-2

1

8

High-throughput

0.481

High

1399329

MAGD1
Melanoma-associated antigen D1

1

6

High-throughput

0.481

High

352792

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.460

High

1193124

PKHN1
Pleckstrin homology domain-containing family N member 1

1

1

Small-scale

0.437

High

1258676

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025