Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
UBA1
Ubiquitin-like modifier-activating enzyme 1 |
10 |
19 |
Small-scale |
0.972 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
7 |
20 |
Small-scale |
0.967 | High |
|
|
OTUB1
Ubiquitin thioesterase OTUB1 |
6 |
11 |
Small-scale |
0.938 | High |
|
|
RN167
E3 ubiquitin-protein ligase RNF167 |
5 |
20 |
Small-scale |
0.928 | High |
|
|
RNF25
E3 ubiquitin-protein ligase RNF25 |
4 |
14 |
High-throughput |
0.912 | High |
|
|
BRCA1
Breast cancer type 1 susceptibility protein |
4 |
20 |
Small-scale |
0.901 | High |
|
|
TRI23
E3 ubiquitin-protein ligase TRIM23 |
4 |
7 |
Small-scale |
0.896 | High |
|
|
TRI32
E3 ubiquitin-protein ligase TRIM32 |
4 |
20 |
Small-scale |
0.896 | High |
|
|
CHIP
E3 ubiquitin-protein ligase CHIP |
4 |
15 |
Small-scale |
0.888 | High |
|
|
RING2
E3 ubiquitin-protein ligase RING2 |
3 |
20 |
Small-scale |
0.873 | High |
|
|
TRI18
E3 ubiquitin-protein ligase Midline-1 |
3 |
20 |
Small-scale |
0.870 | High |
|
|
RN111
E3 ubiquitin-protein ligase Arkadia |
3 |
20 |
High-throughput |
0.867 | High |
|
|
RNF4
E3 ubiquitin-protein ligase RNF4 |
3 |
20 |
Small-scale |
0.857 | High |
|
|
UB2E1
Ubiquitin-conjugating enzyme E2 E1 |
3 |
17 |
Small-scale |
0.845 | High |
|
|
ITCH
E3 ubiquitin-protein ligase Itchy homolog |
3 |
20 |
Small-scale |
0.845 | High |
|
|
ZNRF1
E3 ubiquitin-protein ligase ZNRF1 |
2 |
20 |
High-throughput |
0.843 | High |
|
|
RNF14
E3 ubiquitin-protein ligase RNF14 |
2 |
20 |
Small-scale |
0.812 | High |
|
|
XIAP
E3 ubiquitin-protein ligase XIAP |
2 |
20 |
Small-scale |
0.800 | High |
|
|
GOLI
E3 ubiquitin-protein ligase RNF130 |
2 |
20 |
Small-scale |
0.800 | High |
|
|
MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1 |
2 |
20 |
Small-scale |
0.800 | High |
|
|
TRIM2
Tripartite motif-containing protein 2 |
2 |
20 |
Small-scale |
0.800 | High |
|
|
RNF12
E3 ubiquitin-protein ligase RLIM |
2 |
20 |
Small-scale |
0.800 | High |
|
|
RN181
E3 ubiquitin-protein ligase RNF181 |
2 |
20 |
Small-scale |
0.800 | High |
|
|
RN114
E3 ubiquitin-protein ligase RNF114 |
2 |
20 |
Small-scale |
0.800 | High |
|
|
RING1
E3 ubiquitin-protein ligase RING1 |
2 |
20 |
Small-scale |
0.793 | High |
|
|
UBE3A
Ubiquitin-protein ligase E3A |
2 |
20 |
Small-scale |
0.793 | High |
|
|
IPO11
Importin-11 |
2 |
3 |
Small-scale |
0.793 | High |
|
|
RNF5
E3 ubiquitin-protein ligase RNF5 |
2 |
20 |
Small-scale |
0.785 | High |
|
|
PRKN
E3 ubiquitin-protein ligase parkin |
2 |
20 |
Small-scale |
0.778 | High |
|
|
NED4L
E3 ubiquitin-protein ligase NEDD4-like |
2 |
20 |
Small-scale |
0.778 | High |
|
|
TRI17
E3 ubiquitin-protein ligase TRIM17 |
2 |
20 |
Small-scale |
0.767 | High |
|
|
RNF11
RING finger protein 11 |
1 |
20 |
High-throughput |
0.762 | High |
|
|
UBR5
E3 ubiquitin-protein ligase UBR5 |
2 |
20 |
Small-scale |
0.757 | High |
|
|
CNOT4
CCR4-NOT transcription complex subunit 4 |
2 |
11 |
Small-scale |
0.754 | High |
|
|
ZNRF2
E3 ubiquitin-protein ligase ZNRF2 |
2 |
20 |
Small-scale |
0.754 | High |
|
|
HERC5
E3 ISG15--protein ligase HERC5 |
2 |
20 |
Small-scale |
0.743 | High |
|
|
CBL
E3 ubiquitin-protein ligase CBL |
1 |
12 |
Small-scale |
0.740 | High |
|
|
BRE1A
E3 ubiquitin-protein ligase BRE1A |
1 |
13 |
Small-scale |
0.724 | High |
|
|
TRIM1
Probable E3 ubiquitin-protein ligase MID2 |
1 |
20 |
Small-scale |
0.713 | High |
|
|
RO52
E3 ubiquitin-protein ligase TRIM21 |
1 |
20 |
Small-scale |
0.710 | High |
|
|
TRAF6
TNF receptor-associated factor 6 |
1 |
20 |
High-throughput |
0.710 | High |
|
|
RNF13
E3 ubiquitin-protein ligase RNF13 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
MGRN1
E3 ubiquitin-protein ligase MGRN1 |
1 |
6 |
High-throughput |
0.698 | High |
|
|
RNF37
RING finger protein 37 |
1 |
5 |
High-throughput |
0.698 | High |
|
|
ARI2
E3 ubiquitin-protein ligase ARIH2 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
MKRN3
E3 ubiquitin-protein ligase makorin-3 |
1 |
14 |
High-throughput |
0.698 | High |
|
|
RNF43
E3 ubiquitin-protein ligase RNF43 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
RFWD3
E3 ubiquitin-protein ligase RFWD3 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
LRSM1
E3 ubiquitin-protein ligase LRSAM1 |
1 |
6 |
High-throughput |
0.698 | High |
|
|
ARK2C
E3 ubiquitin-protein ligase ARK2C |
1 |
20 |
High-throughput |
0.698 | High |
|
|
DZIP3
E3 ubiquitin-protein ligase DZIP3 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
RNF10
E3 ubiquitin-protein ligase RNF10 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
DTX3
Probable E3 ubiquitin-protein ligase DTX3 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
DTX3L
E3 ubiquitin-protein ligase DTX3L |
1 |
20 |
High-throughput |
0.698 | High |
|
|
ZNRF4
E3 ubiquitin-protein ligase ZNRF4 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
RN166
E3 ubiquitin-protein ligase RNF166 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
CHFR
E3 ubiquitin-protein ligase CHFR |
1 |
20 |
High-throughput |
0.698 | High |
|
|
RMD5B
E3 ubiquitin-protein transferase RMND5B |
1 |
6 |
High-throughput |
0.698 | High |
|
|
RN185
E3 ubiquitin-protein ligase RNF185 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
BIRC8
Baculoviral IAP repeat-containing protein 8 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
RN150
RING finger protein 150 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
RN115
E3 ubiquitin-protein ligase RNF115 |
1 |
20 |
High-throughput |
0.698 | High |
|
|
COP1
E3 ubiquitin-protein ligase COP1 |
1 |
10 |
High-throughput |
0.691 | High |
|
|
RNF8
E3 ubiquitin-protein ligase RNF8 |
1 |
20 |
Small-scale |
0.680 | High |
|
|
DET1
DET1 homolog |
3 |
3 |
Small-scale |
0.667 | High |
|
|
RNF26
E3 ubiquitin-protein ligase RNF26 |
1 |
20 |
High-throughput |
0.656 | High |
|
|
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
TRI13
E3 ubiquitin-protein ligase TRIM13 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
BRE1B
E3 ubiquitin-protein ligase BRE1B |
1 |
13 |
Small-scale |
0.647 | High |
|
|
TRIM3
Tripartite motif-containing protein 3 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
UBC
Polyubiquitin-C [Cleaved into: Ubiquitin] |
1 |
20 |
Small-scale |
0.647 | High |
|
|
UBA7
Ubiquitin-like modifier-activating enzyme 7 |
1 |
19 |
Small-scale |
0.647 | High |
|
|
RBX1
E3 ubiquitin-protein ligase RBX1 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
MDM2
E3 ubiquitin-protein ligase Mdm2 |
1 |
14 |
Small-scale |
0.647 | High |
|
|
CUL3
Cullin-3 |
1 |
16 |
Small-scale |
0.647 | High |
|
|
RN168
E3 ubiquitin-protein ligase RNF168 |
1 |
7 |
Small-scale |
0.647 | High |
|
|
RN169
E3 ubiquitin-protein ligase RNF169 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
RN128
E3 ubiquitin-protein ligase RNF128 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
RNF34
E3 ubiquitin-protein ligase RNF34 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
RNF31
E3 ubiquitin-protein ligase RNF31 |
1 |
20 |
Small-scale |
0.647 | High |
|
|
TOPRS
E3 ubiquitin-protein ligase Topors |
1 |
6 |
Small-scale |
0.647 | High |
|
|
UBP7
Ubiquitin carboxyl-terminal hydrolase 7 |
2 |
6 |
Small-scale |
0.634 | High |
|
|
ATX1
Ataxin-1 |
2 |
1 |
Small-scale |
0.631 | High |
|
|
TRIB2
Tribbles homolog 2 |
2 |
5 |
High-throughput |
0.628 | High |
|
|
TRIB1
Tribbles homolog 1 |
2 |
6 |
High-throughput |
0.628 | High |
|
|
RN103
E3 ubiquitin-protein ligase RNF103 |
1 |
20 |
Small-scale |
0.621 | High |
|
|
TRI50
E3 ubiquitin-protein ligase TRIM50 |
1 |
20 |
Small-scale |
0.621 | High |
|
|
BIRC7
Baculoviral IAP repeat-containing protein 7 |
1 |
20 |
Small-scale |
0.621 | High |
|
|
TRI45
E3 ubiquitin-protein ligase TRIM45 |
1 |
20 |
Small-scale |
0.621 | High |
|
|
TRI39
E3 ubiquitin-protein ligase TRIM39 |
2 |
20 |
High-throughput |
0.619 | High |
|
|
H2AY
Core histone macro-H2A.1 |
1 |
6 |
Small-scale |
0.618 | High |
|
|
H2AZ
Histone H2A.Z |
1 |
6 |
Small-scale |
0.618 | High |
|
|
UBE2H
Ubiquitin-conjugating enzyme E2 H |
1 |
17 |
High-throughput |
0.618 | High |
|
|
PCGF5
Polycomb group RING finger protein 5 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
DTL
Denticleless protein homolog |
1 |
9 |
Small-scale |
0.618 | High |
|
|
BARD1
BRCA1-associated RING domain protein 1 |
2 |
11 |
Small-scale |
0.602 | High |
|
|
MARH7
E3 ubiquitin-protein ligase MARCHF7 |
2 |
16 |
Small-scale |
0.602 | High |
|
|
RN220
E3 ubiquitin-protein ligase RNF220 |
1 |
7 |
High-throughput |
0.590 | High |
|
|
MBD5
Methyl-CpG-binding domain protein 5 |
2 |
0 |
High-throughput |
0.585 | High |
|
|
RN122
RING finger protein 122 |
1 |
20 |
Small-scale |
0.579 | High |
|
|
UBR7
Putative E3 ubiquitin-protein ligase UBR7 |
2 |
0 |
Small-scale |
0.577 | High |
|
|
PAF1
RNA polymerase II-associated factor 1 homolog |
1 |
0 |
Small-scale |
0.561 | High |
|
|
TRI11
E3 ubiquitin-protein ligase TRIM11 |
1 |
20 |
Small-scale |
0.552 | High |
|
|
M3K1
Mitogen-activated protein kinase kinase kinase 1 |
1 |
12 |
High-throughput |
0.541 | High |
|
|
MARH3
E3 ubiquitin-protein ligase MARCHF3 |
1 |
20 |
High-throughput |
0.541 | High |
|
|
CAPS2
Calcium-dependent secretion activator 2 |
1 |
6 |
High-throughput |
0.541 | High |
|
|
DTX1
E3 ubiquitin-protein ligase DTX1 |
1 |
20 |
High-throughput |
0.541 | High |
|
|
RN152
E3 ubiquitin-protein ligase RNF152 |
1 |
20 |
High-throughput |
0.541 | High |
|
|
MKS1
Tectonic-like complex member MKS1 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
NEK4
Serine/threonine-protein kinase Nek4 |
1 |
4 |
High-throughput |
0.536 | High |
|
|
SIK1
Serine/threonine-protein kinase SIK1 |
1 |
2 |
High-throughput |
0.536 | High |
|
|
CTR9
RNA polymerase-associated protein CTR9 homolog |
1 |
2 |
Small-scale |
0.536 | High |
|
|
STK40
Serine/threonine-protein kinase 40 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
LEO1
RNA polymerase-associated protein LEO1 |
1 |
2 |
Small-scale |
0.536 | High |
|
|
ID2
DNA-binding protein inhibitor ID-2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
CLUA1
Clusterin-associated protein 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
EPS15
Epidermal growth factor receptor substrate 15 |
1 |
4 |
Small-scale |
0.501 | High |
|
|
TF65
Transcription factor p65 |
1 |
7 |
Small-scale |
0.501 | High |
|
|
TIF1B
Transcription intermediary factor 1-beta |
1 |
20 |
Small-scale |
0.501 | High |
|
|
UVSSA
UV-stimulated scaffold protein A |
1 |
4 |
Small-scale |
0.501 | High |
|
|
JADE1
Protein Jade-1 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
NHLC1
E3 ubiquitin-protein ligase NHLRC1 |
1 |
20 |
Small-scale |
0.501 | High |
|
|
ASXL2
Putative Polycomb group protein ASXL2 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
TRI69
E3 ubiquitin-protein ligase TRIM69 |
1 |
20 |
Small-scale |
0.501 | High |
|
|
UBS3B
Ubiquitin-associated and SH3 domain-containing protein B |
1 |
6 |
Small-scale |
0.501 | High |
|
|
DPOLM
DNA-directed DNA/RNA polymerase mu |
1 |
7 |
Small-scale |
0.501 | High |
|
|
MARH5
E3 ubiquitin-protein ligase MARCHF5 |
1 |
6 |
Small-scale |
0.501 | High |
|
|
MARH2
E3 ubiquitin-protein ligase MARCHF2 |
1 |
20 |
Small-scale |
0.501 | High |
|
|
HDAC6
Protein deacetylase HDAC6 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
DPOLL
DNA polymerase lambda |
1 |
7 |
Small-scale |
0.501 | High |
|
|
FBX2
F-box only protein 2 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
TRI33
E3 ubiquitin-protein ligase TRIM33 |
1 |
20 |
Small-scale |
0.501 | High |
|
|
FBX7
F-box only protein 7 |
1 |
3 |
High-throughput |
0.501 | High |
|
|
TRI38
E3 ubiquitin-protein ligase TRIM38 |
1 |
20 |
Small-scale |
0.481 | High |
|
|
TRI37
E3 ubiquitin-protein ligase TRIM37 |
1 |
20 |
Small-scale |
0.481 | High |
|
|
TRI27
Zinc finger protein RFP |
1 |
20 |
Small-scale |
0.481 | High |
|
|
UFM1
Ubiquitin-fold modifier 1 |
1 |
5 |
High-throughput |
0.481 | High |
|
|
ZNG1E
Zinc-regulated GTPase metalloprotein activator 1E |
1 |
1 |
High-throughput |
0.481 | High |
|
|
TRIM7
E3 ubiquitin-protein ligase TRIM7 |
1 |
20 |
Small-scale |
0.481 | High |
|
|
BRD4
Bromodomain-containing protein 4 |
1 |
7 |
High-throughput |
0.479 | High |
|
|
TCTP
Translationally-controlled tumor protein |
1 |
4 |
High-throughput |
0.479 | High |
|
|
1433B
14-3-3 protein beta/alpha |
1 |
1 |
Small-scale |
0.479 | High |
|
|
NR2C2
Nuclear receptor subfamily 2 group C member 2 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
SQSTM
Sequestosome-1 |
1 |
18 |
High-throughput |
0.479 | High |
|
|
NF2L2
Nuclear factor erythroid 2-related factor 2 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
SNX27
Sorting nexin-27 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
DDA1
DET1- and DDB1-associated protein 1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
H10
Histone H1.0 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
FA12
Coagulation factor XII |
1 |
5 |
Small-scale |
0.457 | High |
|
|
TRI29
Tripartite motif-containing protein 29 |
1 |
20 |
Small-scale |
0.457 | High |
|
|
UFL1
E3 UFM1-protein ligase 1 |
1 |
5 |
High-throughput |
0.457 | High |
|
|
ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C |
1 |
1 |
High-throughput |
0.457 | High |
|
|
ARRD1
Arrestin domain-containing protein 1 |
1 |
7 |
High-throughput |
0.457 | High |
|
|
ASF1B
Histone chaperone ASF1B |
1 |
1 |
High-throughput |
0.457 | High |
|
|
LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2 |
1 |
6 |
High-throughput |
0.445 | High |
|
|
CE170
Centrosomal protein of 170 kDa |
1 |
2 |
High-throughput |
0.445 | High |
|
|
PKHA4
Pleckstrin homology domain-containing family A member 4 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
PNT87
Transcriptional regulator PINT87aa |
1 |
0 |
Small-scale |
0.426 | High |
|
|
PAEP
Glycodelin |
1 |
0 |
High-throughput |
0.282 | High |
|
|
ROBO3
Roundabout homolog 3 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 |
1 |
0 |
High-throughput |
0.238 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
