HitPredict

Interactor 1: NIBA2 (Q96TA1)
Protein Niban 2 (Meg-3) (Melanoma invasion by ERK) (MINERVA) (Niban-like protein 1) (Protein FAM129B)
Gene: NIBAN2

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 1620
+	Hs
		464037 NIBA2_HUMAN (1-746): 0: 1176: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		710882 NIBA2_HUMAN (1-746): 0: 1176: 100.00		EPHB2_HUMAN (938-1436): 1.28e-127: 427: 23.26
+	Hs
		439832 NIBA2_HUMAN (1-746): 0: 1176: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465623 NIBA2_HUMAN (1-746): 0: 1176: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		412483 NIBA2_HUMAN (1-746): 0: 1176: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		1157038 NIBA2_HUMAN (1-746): 0: 1176: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541650 NIBA2_HUMAN (1-746): 0: 1176: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07