HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: NIBA2 (Q96TA1)
Protein Niban 2 (Meg-3) (Melanoma invasion by ERK) (MINERVA) (Niban-like protein 1) (Protein FAM129B)
Gene: NIBAN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043066 - negative regulation of apoptotic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1367 Hs			1 746
+	Hs
		439832 INSR_HUMAN (32-1365): 0: 1242: 56.39		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		710882 EPHB2_HUMAN (462-1342): 0: 572: 20.45		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		932120 EPHA4_HUMAN (655-1342): 0: 565: 23.12		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		1147412 EPHA7_HUMAN (666-1342): 2.07e-180: 563: 23.58		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		931884 EPHA5_HUMAN (666-1275): 6.36e-176: 552: 24.01		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		710443 EPHA2_HUMAN (653-1304): 1.9e-165: 523: 23.93		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		1403705 ALK_HUMAN (939-1304): 2.53e-75: 278: 39.12		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		412483 NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		541650 FGFR1_HUMAN (972-1266): 1.33e-64: 238: 39.54		NIBA2_HUMAN (1-746): 0: 1176: 100.00
+	Hs
		1157038 NTRK3_HUMAN (977-1262): 5.77e-64: 236: 39.16		NIBA2_HUMAN (1-746): 0: 1176: 100.00