HitPredict

Interactor 1: PMT3 (O13351)
Ubiquitin-like protein pmt3/smt3
Gene: PMT3

Interactor 2: NESP1 (O42980)
NEDD8-specific protease 1 (EC 3.4.22.-)
Gene: nep1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22730331
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Peptidase_C48~Rad60-SLD
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Sp			1 420
+	Sp
		140841 PMT3_SCHPO (1-117): 6.25e-54: 166: 100.00		ULP1_SCHPO (1-214): 1.88e-53: 188: 15.91
+	Hs
		879158 SUMO3_HUMAN (21-111): 3.28e-40: 130: 50.55		SENP1_HUMAN (2-215): 5.65e-66: 223: 16.37
+	Hs
		902778 SUMO2_HUMAN (21-111): 1.14e-39: 129: 50.00		SENP1_HUMAN (2-215): 5.65e-66: 223: 16.37
+	Hs
		879156 SUMO3_HUMAN (21-111): 3.28e-40: 130: 50.55		SENP2_HUMAN (3-215): 3.76e-64: 217: 16.44
+	Xl
		1151579 SMO2B_XENLA (21-112): 7.8e-40: 129: 49.46		Q804S7_XENLA (2-215): 9.7e-64: 217: 15.93
+	Hs
		902760 SUMO2_HUMAN (21-111): 1.14e-39: 129: 50.00		SENP2_HUMAN (3-215): 3.76e-64: 217: 16.44
+	Hs
		928203 SUMO1_HUMAN (9-111): 4.82e-36: 120: 48.54		SENP2_HUMAN (3-215): 3.76e-64: 217: 16.44
+	Sp
		140818 PMT3_SCHPO (1-117): 6.25e-54: 166: 100.00		ULP2_SCHPO (11-222): 2.12e-43: 162: 12.41
+	Xl
		1140103 SMO2B_XENLA (21-112): 7.8e-40: 129: 49.46		Q5XG28_XENLA (6-215): 3.63e-56: 193: 17.81
+	Hs
		902753 SUMO2_HUMAN (21-111): 1.14e-39: 129: 50.00		SENP3_HUMAN (6-215): 2.02e-54: 191: 16.90
+	Dm
		332584 O97102_DROME (25-112): 5.33e-39: 127: 52.27		Q9VWK5_DROME (7-213): 1.43e-51: 188: 11.98
+	Xl
		78631 SMO2B_XENLA (21-112): 7.8e-40: 129: 49.46		B6RQN8_XENLA (6-215): 1.78e-51: 185: 16.36
+	Hs
		879147 SUMO3_HUMAN (21-111): 3.28e-40: 130: 50.55		SENP5_HUMAN (6-215): 1.27e-49: 181: 15.98
+	Hs
		902714 SUMO2_HUMAN (21-111): 1.14e-39: 129: 50.00		SENP5_HUMAN (6-215): 1.27e-49: 181: 15.98
+	Hs
		902739 SUMO2_HUMAN (21-111): 1.14e-39: 129: 50.00		SENP7_HUMAN (15-216): 1.28e-39: 153: 10.28
+	Mm
		1160381 SUMO3_MOUSE (21-112): 1.42e-41: 134: 50.00		SENP6_MOUSE (110-229): 3.22e-23: 104: 16.67
+	Xl
		80968 SMO2B_XENLA (21-112): 7.8e-40: 129: 49.46		B7TYL1_XENLA (13-118): 3.57e-24: 107: 14.88
+	Xl
		80969 SMO2B_XENLA (21-112): 7.8e-40: 129: 49.46		B7TYL2_XENLA (118-222): 1.99e-14: 77.5: 11.97
+	Hs
		902747 SUMO2_HUMAN (21-111): 1.14e-39: 129: 50.00		SENP6_HUMAN (110-216): 1.15e-11: 69: 16.81
+	Hs
		928190 SUMO1_HUMAN (9-111): 4.82e-36: 120: 48.54		SENP6_HUMAN (110-216): 1.15e-11: 69: 16.81