HitPredict

Interactor 1: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Interactor 2: NLRP1 (Q9C000)
NACHT, LRR and PYD domains-containing protein 1 (EC 3.4.-.-) (EC 3.6.4.-) (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]
Gene: NLRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36332009
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 1473
+	Hs
		997113 TBA4A_HUMAN (1-448): 0: 724: 96.21		NLRP1_HUMAN (1-1473): 0: 1501: 100.00
+	Hs
		1259480 TBA1A_HUMAN (1-439): 0: 715: 99.09		NLRP1_HUMAN (1-1473): 0: 1501: 100.00
+	Hs
		997497 TBB4B_HUMAN (1-437): 0: 697: 40.73		NLRP1_HUMAN (1-1473): 0: 1501: 100.00
+	Hs
		1360119 TBA1C_HUMAN (1-449): 0: 733: 100.00		NALP7_HUMAN (207-1112): 1.19e-160: 512: 24.92
+	Hs
		457588 TBB5_HUMAN (1-439): 0: 699: 41.00		NALP7_HUMAN (207-1112): 1.19e-160: 512: 24.92
+	Hs
		457337 TBB5_HUMAN (1-439): 0: 699: 41.00		NLRP6_HUMAN (939-1119): 2.1e-09: 64.4: 13.54