HitPredict

Interactor 1: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Interactor 2: DCA13 (Q9NV06)
DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)
Gene: DCAF13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.80	0.797

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Sof1~WD40, WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 315 Hs			1 445
+	Dm
		1267367 Q9VYQ9_DROME (2-313): 9.36e-88: 272: 21.78		Q7KLW9_DROME (30-312): 6.45e-70: 231: 20.27
+	Hs
		1387527 WDR83_HUMAN (1-315): 9.92e-102: 302: 100.00		SNR40_HUMAN (311-439): 9.77e-24: 103: 6.77
+	Hs
		1412050 WDR83_HUMAN (1-315): 9.92e-102: 302: 100.00		PRP19_HUMAN (169-372): 1.16e-22: 102: 13.53
+	Hs
		921980 FBXW7_HUMAN (2-258): 1.36e-67: 225: 23.02		COPA_HUMAN (36-341): 5.65e-46: 172: 16.67
+	Mm
		988931 LIS1_MOUSE (63-312): 6.04e-76: 239: 17.71		LIS1_MOUSE (4-184): 9.82e-43: 157: 15.87
+	Hs
		845250 LIS1_HUMAN (63-312): 7.66e-76: 239: 17.71		LIS1_HUMAN (4-184): 1.17e-42: 156: 15.87
+	Dm
		1463921 Q9VYQ9_DROME (2-313): 9.36e-88: 272: 21.78		WDS_DROME (311-444): 6.89e-28: 115: 9.49
+	Hs
		222461 PLRG1_HUMAN (2-312): 6.04e-86: 268: 23.15		WDR5_HUMAN (311-444): 6e-28: 115: 9.49
+	Hs
		251027 PRP17_HUMAN (8-304): 8.85e-88: 275: 23.40		SNR40_HUMAN (311-439): 9.77e-24: 103: 6.77
+	Hs
		251048 PRP17_HUMAN (8-304): 8.85e-88: 275: 23.40		PRP19_HUMAN (169-372): 1.16e-22: 102: 13.53
+	Hs
		222515 PLRG1_HUMAN (2-312): 6.04e-86: 268: 23.15		SNR40_HUMAN (311-439): 9.77e-24: 103: 6.77
+	Hs
		222547 PLRG1_HUMAN (2-312): 6.04e-86: 268: 23.15		PRP19_HUMAN (169-372): 1.16e-22: 102: 13.53
+	Dm
		1463899 WDS_DROME (2-266): 7.93e-81: 251: 22.26		WDS_DROME (311-444): 6.89e-28: 115: 9.49
+	Hs
		845264 LIS1_HUMAN (63-312): 7.66e-76: 239: 17.71		WDR5_HUMAN (311-444): 6e-28: 115: 9.49
+	Hs
		921858 WDR5_HUMAN (140-312): 2.14e-52: 176: 23.60		COPA_HUMAN (36-341): 5.65e-46: 172: 16.67
+	Hs
		965141 FBXW7_HUMAN (2-258): 1.36e-67: 225: 23.02		WDR5_HUMAN (311-444): 6e-28: 115: 9.49
+	Dm
		1463923 FBXW7_DROME (2-258): 1.52e-61: 213: 21.81		WDS_DROME (311-444): 6.89e-28: 115: 9.49
+	Hs
		1380250 FBXW7_HUMAN (2-258): 1.36e-67: 225: 23.02		PRP19_HUMAN (169-372): 1.16e-22: 102: 13.53
+	Hs
		964797 WDR5_HUMAN (140-312): 2.14e-52: 176: 23.60		WDR5_HUMAN (311-444): 6e-28: 115: 9.49