Interactor 1: THUM3 (Q9BV44)
tRNA (guanine(6)-N(2))-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3) (tRNA(Trp) (guanine(7)-N(2))-methyltransferase THUMP3) (EC 2.1.1.-)
Gene: THUMPD3
Interactor 2: TR112 (Q9UI30)
Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog)
Gene: TRMT112
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.946 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32296183, 33961781, unassigned1304, 34948388, unassigned3799 |
| Identification Methods | affinity chromatography technology, two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Trm112p~UPF0020 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030488 - tRNA methylation |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
