Protein: THUM2
U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 (EC 2.1.1.-) (THUMP domain-containing protein 2)

Gene: THUM2, THUMPD2
Organism: Homo sapiens
Interactions: 11
UniProt ID: Q9BTF0

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0016423 - tRNA (guanine) methyltransferase activity
GO:0030488 - tRNA methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413523

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

5

Small-scale

0.646

High

1388633

SPDLY
Protein Spindly

2

0

High-throughput

0.602

High

74584

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.515

High

1413525

RALY
RNA-binding protein Raly

1

1

High-throughput

0.515

High

1413526

NOP58
Nucleolar protein 58

1

2

High-throughput

0.515

High

1156322

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.486

High

1413524

XPO7
Exportin-7

1

3

High-throughput

0.479

High

660150

COF1
Cofilin-1

1

0

High-throughput

0.458

High

1413522

LACRT
Extracellular glycoprotein lacritin

2

0

High-throughput

0.328

High

301671

WFS1
Wolframin

1

0

High-throughput

0.268

Low

844226

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025