HitPredict

Interactor 1: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Interactor 2: X5DP35 (X5DP35)
NudE neurodevelopment protein 1 isoform A
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	24722188
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NUDE_C~NUDE_C
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005819 - spindle GO:0005874 - microtubule GO:0008017 - microtubule binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 339
+	Hs
		1428189 NDEL1_HUMAN (1-345): 1.81e-67: 217: 100.00		NDEL1_HUMAN (3-276): 5.37e-55: 184: 59.21
+	Hs
		1428201 NDEL1_HUMAN (1-345): 1.81e-67: 217: 100.00		NDE1_HUMAN (1-276): 1.58e-54: 183: 96.01
+	Mm
		1424414 NDEL1_MOUSE (1-345): 7.08e-67: 215: 95.94		NDEL1_MOUSE (3-276): 7.63e-55: 184: 58.85
+	Hs
		116775 NDEL1_HUMAN (1-345): 1.81e-67: 217: 100.00		I3L3G9_HUMAN (1-269): 8.09e-49: 167: 98.51
+	Xl
		1226381 NDE1A_XENLA (1-345): 4.46e-46: 162: 50.99		NDE1A_XENLA (2-276): 2.64e-49: 170: 71.58
+	Hs
		1452072 NDE1_HUMAN (3-321): 2.96e-41: 149: 55.25		NDE1_HUMAN (1-276): 1.58e-54: 183: 96.01
+	Hs
		1428234 NDEL1_HUMAN (1-345): 1.81e-67: 217: 100.00		X5DRF9_HUMAN (1-79): 2.01e-15: 72.6: 100.00
+	Hs
		1415821 EP15R_HUMAN (7-325): 7.03e-42: 157: 12.81		KIFC1_HUMAN (10-242): 9.12e-29: 118: 13.31
+	Hs
		157495 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		CYTSA_HUMAN (2-255): 1.06e-36: 142: 18.69
+	An
		267925 NDE1_EMENI (16-326): 3.81e-29: 119: 28.70		NDE1_EMENI (1-265): 3.32e-32: 128: 29.37
+	Hs
		772647 MYH11_HUMAN (2-223): 2.18e-26: 112: 18.92		MYH9_HUMAN (2-212): 2.71e-30: 123: 18.48
+	Hs
		157026 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		MYH11_HUMAN (2-210): 1.3e-30: 124: 18.66
+	Hs
		157020 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		MYH9_HUMAN (2-212): 2.71e-30: 123: 18.48
+	Hs
		773112 MYH11_HUMAN (2-223): 2.18e-26: 112: 18.92		MYH10_HUMAN (2-212): 5.1e-26: 111: 19.43
+	Hs
		157021 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		MYH10_HUMAN (2-212): 5.1e-26: 111: 19.43
+	Rn
		236526 MRCKA_RAT (2-209): 6.55e-27: 113: 18.22		MRCKA_RAT (14-201): 1.55e-12: 70.7: 16.24
+	Hs
		776829 MYH11_HUMAN (2-223): 2.18e-26: 112: 18.92		MYH14_HUMAN (2-211): 2.76e-12: 69.9: 17.62
+	Rn
		236530 MRCKA_RAT (2-209): 6.55e-27: 113: 18.22		MRCKB_RAT (5-188): 1.61e-09: 61.5: 16.13