HitPredict

Interactor 1: CUL1 (O13790)
Cullin-1 (Cul-1) (Cell division control 53 homolog)
Gene: CUL1

Interactor 2: RBX1 (O13959)
RING-box protein pip1 (RING-box protein 1) (Pop-interacting protein 1)
Gene: pip1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 12167173, 11337588, 23535663
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0043224 - nuclear SCF ubiquitin ligase complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 767
Sp

1 107
+ Mm
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+ Hs
+ At
+ Mm
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+ Dm
+ At
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+ Dm
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+ Dm
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+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024