HitPredict

Interactor 1: EHD4 (Q9H223)
EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4)
Gene: EHD4

Interactor 2: EHD1 (Q9H4M9)
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)
Gene: EHD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 30833792, 38334954, 31839598
Identification Methods affinity chromatography technology, cross-linking study, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF5600~Dynamin_N, DUF5600~EHD_N, Dynamin_N~Dynamin_N, Dynamin_N~EHD_N
Common GO terms GO:0005509 - calcium ion binding
GO:0005524 - ATP binding
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005769 - early endosome
and 13 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 541
Hs

1 534
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Ce
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025