HitPredict

Interactor 1: VPS11 (Q9H270)
Vacuolar protein sorting-associated protein 11 homolog (hVPS11) (RING finger protein 108)
Gene: VPS11

Interactor 2: PKHM1 (Q9Y4G2)
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) (162 kDa adapter protein) (AP162)
Gene: PLEKHM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28325809, 33452816, 38448435
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0008270 - zinc ion binding GO:0031902 - late endosome membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 1056
+	Hs
		1454287 VPS18_HUMAN (105-847): 1.09e-158: 493: 16.16		PKHM1_HUMAN (1-1056): 0: 1398: 100.00
+	Hs
		888824 VPS41_HUMAN (334-865): 4.63e-90: 307: 17.02		PKHM1_HUMAN (1-1056): 0: 1398: 100.00
+	Hs
		1394874 VPS39_HUMAN (290-851): 9.9e-84: 290: 13.72		PKHM1_HUMAN (1-1056): 0: 1398: 100.00