Interactor 1: Q9N6D8 (Q9N6D8)
GH11591p (P53, isoform A) (P53, isoform C) (Transcription factor) (p53 tumor suppressor-like protein) (p53-like regulator of apoptosis and cell cycle)
Gene: p53

Interactor 2: TOPRS (Q9V8P9)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (dTopors)
Gene: Topors

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 14871887, 15710747
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 385
Dm

1 1038
+ Hs
+ Mm
+ Dm

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Last updated: 11Aug2025