HitPredict

Interactor 1: ZCC17 (Q9NP64)
Zinc finger CCHC domain-containing protein 17 (Nucleolar protein of 40 kDa) (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein)
Gene: ZCCHC17

Interactor 2: ZCC17 (Q9NP64)
Zinc finger CCHC domain-containing protein 17 (Nucleolar protein of 40 kDa) (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein)
Gene: ZCCHC17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	S1~S1
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0008270 - zinc ion binding GO:0022625 - cytosolic large ribosomal subunit GO:0043489 - RNA stabilization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 241
+	Sc
		664573 PRP22_YEAST (5-236): 6.27e-46: 165: 23.11		PRP22_YEAST (5-236): 6.27e-46: 165: 23.11
+	Hs
		1128002 DHX8_HUMAN (1-241): 2.3e-31: 123: 18.07		DHX8_HUMAN (1-241): 2.3e-31: 123: 18.07
+	Ec
		861412 YHGF_ECOLI (8-140): 1.8e-27: 111: 23.31		YHGF_ECOLI (8-140): 1.8e-27: 111: 23.31
+	Ec
		421088 PNP_ECOLI (5-94): 1.78e-26: 109: 27.78		PNP_ECOLI (5-94): 1.78e-26: 109: 27.78
+	Sa
		1232804 PNP_STAAR (1-92): 4.7e-20: 90.4: 22.34		PNP_STAAR (1-92): 4.7e-20: 90.4: 22.34
+	Sc
		1050158 RRP5_YEAST (11-219): 2.39e-15: 76.9: 16.82		RRP5_YEAST (11-219): 2.39e-15: 76.9: 16.82
+	Ec
		501370 RS1_ECOLI (16-190): 4.16e-13: 70: 13.89		RS1_ECOLI (16-190): 4.16e-13: 70: 13.89
+	Hp
		939714 RS1_HELPY (14-181): 8.75e-12: 66.2: 18.45		RS1_HELPY (14-181): 8.75e-12: 66.2: 18.45
+	Ec
		501380 RS1_ECOLI (16-190): 4.16e-13: 70: 13.89		RNR_ECOLI (14-85): 2.88e-09: 58.8: 21.69