HitPredict

Interactor 1: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Interactor 2: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 25416956, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SCAN~SCAN, zf-C2H2~zf-C2H2
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005615 - extracellular space
GO:0005634 - nucleus
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 450
Hs

1 450
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Service provided by Combinatics, Japan

Last updated: 11Aug2025