HitPredict

Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2

Interactor 2: STK38 (Q15208)
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)
Gene: STK38

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28216640
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035556 - intracellular signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 198 Hs			1 465
+	Hs
		411727 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		STK38_HUMAN (1-465): 0: 527: 100.00
+	Hs
		433510 YES_HUMAN (15-176): 1.6e-45: 159: 13.53		ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47
+	Hs
		434089 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47
+	Hs
		789133 FRK_HUMAN (3-172): 1.74e-44: 156: 17.24		LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58
+	Hs
		523170 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58
+	Hs
		337568 ABL1_HUMAN (3-173): 4.38e-42: 152: 19.65		LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58
+	Hs
		325610 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48
+	Hs
		412046 FYN_HUMAN (14-172): 9.8e-47: 162: 14.97		AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06
+	Hs
		411908 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		MRCKB_HUMAN (64-463): 2.71e-128: 409: 41.26
+	Hs
		522810 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06
+	Mm
		403418 SRC_MOUSE (1-176): 2.21e-43: 153: 15.76		AKT1_MOUSE (50-447): 2.25e-137: 405: 27.16
+	Hs
		434101 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		MRCKB_HUMAN (64-463): 2.71e-128: 409: 41.26
+	Hs
		433609 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45
+	Hs
		681838 PTK6_HUMAN (1-192): 1.96e-40: 144: 16.58		AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06
+	Hs
		411994 FYN_HUMAN (14-172): 9.8e-47: 162: 14.97		KAPCA_HUMAN (59-418): 5.12e-128: 376: 33.15
+	Hs
		412014 FYN_HUMAN (14-172): 9.8e-47: 162: 14.97		KAPCB_HUMAN (74-418): 6.95e-128: 376: 34.29
+	Hs
		181797 SOCS1_HUMAN (32-198): 8.74e-41: 139: 31.77		KAPCB_HUMAN (74-418): 6.95e-128: 376: 34.29
+	Hs
		411758 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		MRCKA_HUMAN (78-445): 1.93e-90: 303: 45.07
+	Hs
		433818 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		MRCKA_HUMAN (78-445): 1.93e-90: 303: 45.07
+	Hs
		433749 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		ROCK1_HUMAN (70-415): 3.59e-79: 270: 42.90