HitPredict

Interactor 1: RHG33 (O14559)
Rho GTPase-activating protein 33 (Rho-type GTPase-activating protein 33) (Sorting nexin-26) (Tc10/CDC42 GTPase-activating protein)
Gene: ARHGAP33

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 20936779
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RhoGAP
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005938 - cell cortex
GO:0007264 - small GTPase-mediated signal transduction
GO:0019901 - protein kinase binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1287
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024