Protein: PTPC1
Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)

Gene: PTPC1, PTPDC1
Organism: Homo sapiens
Interactions: 71
UniProt ID: A2A3K4

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0060271 - cilium assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

58703

MK01
Mitogen-activated protein kinase 1

5

20

High-throughput

0.926

High

58685

CSKP
Peripheral plasma membrane protein CASK

3

13

High-throughput

0.861

High

58749

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

11

High-throughput

0.783

High

58730

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

6

7

High-throughput

0.732

High

58720

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

5

8

High-throughput

0.718

High

58719

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

5

7

High-throughput

0.716

High

58705

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

4

10

High-throughput

0.694

High

58701

MK03
Mitogen-activated protein kinase 3

1

20

High-throughput

0.691

High

58700

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

58718

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.650

High

58708

ARL2
ADP-ribosylation factor-like protein 2

2

5

High-throughput

0.628

High

58683

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

17

High-throughput

0.618

High

58687

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

8

High-throughput

0.618

High

58727

MAPK3
MAP kinase-activated protein kinase 3

1

3

High-throughput

0.618

High

58704

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

11

High-throughput

0.611

High

58714

DCAF7
DDB1- and CUL4-associated factor 7

2

8

High-throughput

0.611

High

58715

1433G
14-3-3 protein gamma

2

20

High-throughput

0.611

High

58716

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.611

High

58750

FBX3
F-box only protein 3

2

5

High-throughput

0.611

High

58709

CRKL
Crk-like protein

2

10

High-throughput

0.606

High

58706

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.584

High

58691

TIPRL
TIP41-like protein

2

0

High-throughput

0.559

High

58725

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.541

High

58717

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

8

High-throughput

0.536

High

58740

COP1
E3 ubiquitin-protein ligase COP1

1

8

High-throughput

0.536

High

58742

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

13

High-throughput

0.536

High

58688

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

0

High-throughput

0.513

High

58694

HARS1
Histidine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

58713

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.513

High

58697

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.494

High

58731

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

58736

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

58684

PTG3L
Putative protein PTGES3L

1

1

High-throughput

0.479

High

58686

XPO1
Exportin-1

1

18

High-throughput

0.479

High

58689

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

11

High-throughput

0.479

High

58690

FLNB
Filamin-B

1

5

High-throughput

0.479

High

58692

MTA2
Metastasis-associated protein MTA2

1

3

High-throughput

0.479

High

58695

CCNB1
G2/mitotic-specific cyclin-B1

1

3

High-throughput

0.479

High

58696

PRPS3
Ribose-phosphate pyrophosphokinase 3

1

2

High-throughput

0.479

High

58699

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

58702

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

58707

NU214
Nuclear pore complex protein Nup214

1

5

High-throughput

0.479

High

58710

DHYS
Deoxyhypusine synthase

1

2

High-throughput

0.479

High

58711

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.479

High

58712

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

2

High-throughput

0.479

High

58721

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.479

High

58722

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

58723

KIF1A
Kinesin-like protein KIF1A

1

4

High-throughput

0.479

High

58724

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

4

High-throughput

0.479

High

58726

DDB1
DNA damage-binding protein 1

1

6

High-throughput

0.479

High

58728

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

5

High-throughput

0.479

High

58729

NU188
Nucleoporin NUP188

1

1

High-throughput

0.479

High

58733

GPSM1
G-protein-signaling modulator 1

1

7

High-throughput

0.479

High

58738

NUP93
Nuclear pore complex protein Nup93

1

3

High-throughput

0.479

High

58743

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

4

High-throughput

0.479

High

58744

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

12

High-throughput

0.479

High

58746

WDR6
tRNA

1

14

High-throughput

0.479

High

58747

DCA16
DDB1- and CUL4-associated factor 16

1

1

High-throughput

0.479

High

58748

XPO7
Exportin-7

1

13

High-throughput

0.479

High

58698

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.458

High

58745

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.458

High

58739

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

6

High-throughput

0.437

High

58741

POF1B
Protein POF1B

1

1

High-throughput

0.437

High

58751

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.437

High

58752

PDIP2
Polymerase delta-interacting protein 2

1

5

High-throughput

0.437

High

58737

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

58732

BBS12
Chaperonin-containing T-complex member BBS12

1

0

High-throughput

0.279

Low

58693

CASK
Kappa-casein

1

0

High-throughput

0.249

Low

58735

CC28A
Coiled-coil domain-containing protein 28A

1

0

High-throughput

0.249

Low

58734

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025