HitPredict

Interactor 1: MSS4 (Q9VLP3)
Guanine nucleotide exchange factor MSS4 homolog (Guanine nucleotide exchange factor stratum)
Gene: strat

Interactor 2: Q9W5X0 (Q9W5X0)
LD21953p (Rab35, isoform A) (Rab35, isoform B) (Rab35, isoform D)
Gene: Rab35

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.659

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 122 Dm			1 201
+	Dm
		197420 MSS4_DROME (1-122): 7.72e-68: 201: 100.00		O18338_DROME (1-198): 4.69e-86: 254: 46.50
+	Dm
		197103 MSS4_DROME (1-122): 7.72e-68: 201: 100.00		O18332_DROME (1-200): 3.55e-82: 244: 51.71
+	Hs
		866394 MSS4_HUMAN (13-120): 4.19e-60: 182: 39.64		RAB1B_HUMAN (1-200): 1.31e-86: 255: 53.23
+	Hs
		866373 MSS4_HUMAN (13-120): 4.19e-60: 182: 39.64		RAB1A_HUMAN (1-200): 6.69e-86: 253: 52.97
+	Mm
		981414 MSS4_MOUSE (13-120): 1.84e-60: 182: 42.34		RAB1A_MOUSE (1-200): 6.69e-86: 253: 52.97
+	Hs
		866368 MSS4_HUMAN (13-120): 4.19e-60: 182: 39.64		RAB13_HUMAN (1-198): 8.39e-83: 245: 49.50
+	Hs
		866388 MSS4_HUMAN (13-120): 4.19e-60: 182: 39.64		RAB8B_HUMAN (1-200): 1.82e-78: 235: 44.61
+	Hs
		866371 MSS4_HUMAN (13-120): 4.19e-60: 182: 39.64		RAB8A_HUMAN (1-200): 1.1e-77: 233: 45.59
+	Hs
		866372 MSS4_HUMAN (13-120): 4.19e-60: 182: 39.64		RAB10_HUMAN (3-183): 9e-63: 194: 50.55