HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 262
+	Hs
		149112 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33
+	Hs
		148682 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		148692 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Hs
		148763 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37
+	Hs
		148334 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		148894 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PAP1L_HUMAN (6-99): 1.67e-18: 86.3: 21.28
+	Hs
		149282 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37
+	Hs
		148691 CTRO_HUMAN (1-2027): 0: 1212: 100.00		TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91
+	Hs
		964075 KS6B2_HUMAN (57-412): 7.82e-122: 395: 30.44		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Sc
		376578 KAPB_YEAST (77-406): 2.85e-122: 393: 29.59		PABP_YEAST (2-98): 4.25e-20: 91: 24.74
+	Rn
		1144336 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		PABP1_RAT (2-99): 4.73e-19: 88.3: 17.35
+	Hs
		516724 KS6B2_HUMAN (57-412): 7.82e-122: 395: 30.44		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		116962 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35