HitPredict

Interactor 1: Q9VRT7 (Q9VRT7)
U6 snRNA-associated Sm-like protein LSm5
Gene: BcDNA:RE60135

Interactor 2: Q9VTW6 (Q9VTW6)
U6 snRNA-associated Sm-like protein LSm2
Gene: DmelCG10418

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005681 - spliceosomal complex GO:0005688 - U6 snRNP GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 91 Dm			1 95
+	Hs
		1491048 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		LSM2_HUMAN (1-95): 1.9e-35: 117: 91.58
+	Dm
		1479974 Q9VRT7_DROME (1-91): 9.39e-33: 110: 100.00		Q9VKW8_DROME (1-95): 3.06e-32: 111: 28.57
+	Hs
		1491471 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		LSM4_HUMAN (1-87): 5.86e-30: 105: 31.03
+	Hs
		973852 RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30		LSM2_HUMAN (1-95): 1.9e-35: 117: 91.58
+	Dm
		1303484 Q8IMX8_DROME (6-88): 5.69e-26: 93.8: 20.43		Q9VTW6_DROME (1-95): 1.78e-35: 117: 100.00
+	Dm
		1481277 RUXE_DROME (5-91): 6.08e-26: 93.4: 24.18		Q9VTW6_DROME (1-95): 1.78e-35: 117: 100.00
+	Dm
		1303482 Q8IMX8_DROME (6-88): 5.69e-26: 93.8: 20.43		Q9VKW8_DROME (1-95): 3.06e-32: 111: 28.57
+	Dm
		1479970 RUXE_DROME (5-91): 6.08e-26: 93.4: 24.18		Q9VKW8_DROME (1-95): 3.06e-32: 111: 28.57
+	Hs
		973858 RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30		LSM4_HUMAN (1-87): 5.86e-30: 105: 31.03
+	Hs
		974877 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		SMD3_HUMAN (2-88): 5.93e-23: 86.9: 21.84
+	Dm
		1173251 Q9VRT7_DROME (1-91): 9.39e-33: 110: 100.00		RUXF_DROME (3-84): 1.06e-23: 87.7: 26.83
+	Hs
		974093 LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78		RUXF_HUMAN (3-71): 1.13e-22: 85: 31.43
+	Hs
		973682 RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30		SMD1_HUMAN (1-95): 8.67e-28: 99.2: 28.42
+	At
		1319290 Q8LAK5_ARATH (4-88): 9.65e-28: 97.7: 25.84		RUXF_ARATH (3-84): 1.59e-23: 87.3: 32.14
+	At
		1457171 Q9ZV45_ARATH (4-88): 4.94e-27: 96.1: 25.84		RUXF_ARATH (3-84): 1.59e-23: 87.3: 32.14
+	Hs
		973684 RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30		SMD3_HUMAN (2-88): 5.93e-23: 86.9: 21.84
+	Hs
		973678 RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30		RUXF_HUMAN (3-71): 1.13e-22: 85: 31.43
+	Dm
		1173250 RUXE_DROME (5-91): 6.08e-26: 93.4: 24.18		RUXF_DROME (3-84): 1.06e-23: 87.7: 26.83
+	Dm
		232185 RUXE_DROME (5-91): 6.08e-26: 93.4: 24.18		SMD3_DROME (2-74): 1.33e-22: 86.9: 24.66
+	Hs
		973786 RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30		LSM10_HUMAN (3-87): 1.41e-21: 83.4: 25.88