HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000281 - mitotic cytokinesis GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 2364
+	Hs
		149277 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN4_HUMAN (5-2092): 2.42e-155: 540: 52.21
+	Hs
		148171 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58
+	Hs
		148722 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN3_HUMAN (41-776): 4.93e-97: 338: 33.73
+	Hs
		148339 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		148330 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTB1_HUMAN (1359-2356): 5.1e-25: 117: 13.42
+	Hs
		148786 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		148841 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59
+	Hs
		149428 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23
+	Hs
		148142 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Rn
		1144340 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		SPTN2_RAT (2-2318): 0: 636: 61.69
+	Hs
		809184 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		623875 KPCL_HUMAN (1355-1514): 4.34e-12: 73.3: 16.36		PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59